INHIBITION OF MIRNA-212/132 IMPROVES THE REPROGRAMMING OF FIBROBLASTS INTO INDUCED PLURIPOTENT STEM CELLS BY DE-REPRESSING IMPORTANT EPIGENETIC REMODELLING FACTORS

MicroRNAs (miRNAs) repeatedly have been demonstrated to play important roles in the generation of induced Drive Roller pluripotent stem cells (iPSCs).To further elucidate the molecular mechanisms underlying transcription factor-mediated reprogramming we have established a model, which allows for the efficient screening of whole libraries of miRNAs

Abstract Despite global efforts to monitor, mitigate against, and prevent trash (mismanaged solid waste) pollution, no harmonized trash typology system has been widely adopted worldwide.This impedes the merging of datasets and comparative analyses.We addressed this problem by 1) assessing the state of trash typology and comparability, 2) developing

Abstract Background Nonunion of femoral shaft fractures in children is rare, and there is no clear treatment Connector Tubing protocol.In this case report, a pediatric femoral shaft fracture that developed in nonunion due to vitamin deficiency after osteosynthesis, which was successfully treated with vitamin augmentation and replacement with a rigi

While numerous Groceries studies have focused on analyzing various aspects of the carbon (C) budget in forests, there appears to be a lack of comprehensive assessments specifically addressing the impact of stem rot on the C budget of broadleaf tree species, especially in old-growth forests where stem rot is prevalent.One of the main challenges in a